To address the elephant in the room, this guide is NOT updated for Repentance.This guide makes liberal use of grouping various Secrets together so if you cannot find a specific item using Ctrl + F try searching for it's category (the specific location/boss in question for example). I attempt to avoid or hide random spoilers in unrelated Secrets, but you should use Ctrl + F (or whatever it is on Mac) to find a specific Secret if that's what you're here for. This guide does SPOIL EVERYTHING so explore at your own risk. This guide also serves as an achievement guide as every Secret has and achievement and vice versa. So I'm going to go over every single Secret and its unlock method listed in the order that Steam lists them. In their defense, a good chunk of Isaac's unlocks and their descriptions are really self-explanatory, but not everything is and I can imagine trying to unlock all 403 achievements (or Secrets as I will refer to them) can be really overwhelming for a new player. lacking in terms of offering advice or methods to various unlocks. Now that I have 1,000,000%, I discovered how useful having a guide is to completing this game and also noticed that most steam guides and wikis are a bit. I actually got pretty far but came to the conclusion that completing this game is too big of a task to do on pure self-discovery alone. Hi, I am a big fan of The Binding of Isaac: Rebirth (I have 679 hours in the game as of writing this) and I tried my best to complete this game to 1,000,000% without the use of any guides or wikis.
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